2021 Section Alignment
| Section 1 | Section 2 | Section 3 | Section 4 |
| McCaskey | Lebanon | Manheim Central | Annville-Cleona |
| Hempfield | Conestoga Valley | Garden Spot | Pequea Valley |
| Manheim Township | Elizabethtown | Cocalico | Lancaster Catholic* |
| Penn Manor | Ephrata | Donegal* | Columbia |
| Cedar Crest | Solanco | ELCO | Lancaster Mennonite |
| Warwick* | Lampeter-Strasburg† | Northern Lebanon | Lebanon Catholic |
| Octorara |
*2019 Section Champion
†2019 Section Champion and League Champion
2019 Softball Bracket
Current Standings courtesy Lancaster Online
2021 Softball Playoffs
Quarterfinals Saturday, May 15th, Section Champions host
Semifinals Monday, May 17th at Millersville, games at 4:30 and 7
Finals Wednesday, May 19th at Millersville, 7 pm
LL League Softball Chairperson: Anthony Hall, AD, Solanco